Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735408 | 1.00 | MEN1 (0.60) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL29658372 | 0.97 | MEN1 (0.63) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL28735422 | 0.97 | MEN1 (0.63) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL28735420 | 0.96 | MEN1 (0.62) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL29658388 | 0.96 | MEN1 (0.62) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL29658344 | 0.89 | CD274 (0.66) | EPHX2CD274KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL2967384 | 0.89 | CD274 (0.66) | EPHX2CD274KCNH2ALDH1A1CYP1A2 | |
| SCHEMBL28735456 | 0.88 | MEN1 (0.49) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL28735410 | 0.88 | MEN1 (0.49) | MEN1KMT2AEPHX2CD274KCNH2 | |
| SCHEMBL29658406 | 0.85 | MEN1 (0.45) | MEN1KMT2AEPHX2CD274KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478366-A | Pyridone derivative and application thereof in medicine | 海思科医药集团股份有限公司 | 2022-05-13 | — | — | CN | disclosed |