Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19716904 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3580888 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3580885 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3576011 | 0.92 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3570759 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3578260 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3574454 | 0.82 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3577618 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3574209 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTGALR3 | |
| SCHEMBL3577042 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPTGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |