SCHEMBL29658682

SCHEMBL29658682

COc1ccc(C[C@](C)(N)C(=O)O)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
BLM P54132 2/20 0.60
KDM4E B2RXH2 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
POLB P06746 2/20 0.60
GAA P10253 2/20 0.60
MEN1 O00255 1/20 0.60
USP2 O75604 1/20 0.60
EGFR P00533 1/20 0.60
FYN P06241 1/20 0.60
MAPT P10636 1/20 0.60
HPGD P15428 1/20 0.60
ALOX15 P16050 1/20 0.60
APEX1 P27695 1/20 0.60
ADRA1A P35348 1/20 0.60
PTGS2 P35354 1/20 0.60
MTOR P42345 1/20 0.60
RECQL P46063 1/20 0.60
CASP6 P55212 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658681 1.00 ALDH1A1 (0.60) ALDH1A1BLMKDM4ECYP1A2CYP3A4
SCHEMBL6339568 1.00 ALDH1A1 (0.60) ALDH1A1BLMKDM4ECYP1A2CYP3A4
SCHEMBL24534351 1.00 ALDH1A1 (0.60) ALDH1A1BLMKDM4ECYP1A2CYP3A4
SCHEMBL6339567 1.00 ALDH1A1 (0.60) ALDH1A1BLMKDM4ECYP1A2CYP3A4
Hydrochloric Acid SCHEMBL28101234 0.98 ALDH1A1 (0.59) ALDH1A1BLMKDM4ECYP1A2CYP3A4
Hydrochloric Acid SCHEMBL29152364 0.98 ALDH1A1 (0.59) ALDH1A1BLMKDM4ECYP1A2CYP3A4
SCHEMBL27986995 0.98 ALDH1A1 (0.59) ALDH1A1BLMKDM4ECYP1A2CYP3A4
Hydrochloric Acid SCHEMBL27963479 0.98 ALDH1A1 (0.59) ALDH1A1BLMKDM4ECYP1A2CYP3A4
Hydrochloric Acid SCHEMBL30149960 0.98 ALDH1A1 (0.59) ALDH1A1BLMKDM4ECYP1A2CYP3A4
Hydrochloric Acid SCHEMBL28101342 0.97 ALDH1A1 (0.57) ALDH1A1BLMKDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478303-A Method for synthesizing carbidopa 浙江野风药业股份有限公司 2022-05-13 CN disclosed