Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PRDX1 | Q06830 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21989897 | 1.00 | SLC6A2 (0.45) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| Hydrochloric Acid SCHEMBL5874197 | 0.84 | SLC6A2 (0.40) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| Hydrochloric Acid SCHEMBL5874289 | 0.84 | SLC6A2 (0.40) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL4477246 | 0.83 | ALDH1A1 (0.45) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL1515317 | 0.81 | GRIN1 (0.46) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL746867 | 0.81 | ALDH1A1 (0.46) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL19855208 | 0.80 | GRIN1 (0.44) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL27936927 | 0.78 | SLC6A2 (0.46) | SLC6A2GRIN1GRIN2AGRIN2BCHRM2 | |
| SCHEMBL1515509 | 0.78 | GRIN1 (0.47) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 | |
| SCHEMBL748566 | 0.76 | SLC6A2 (0.39) | SLC6A2GRIN1GRIN2AGRIN2BVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118804917-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-114478485-B | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114478485-A | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-13 | — | — | CN | disclosed |