Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547206 | 1.00 | YTHDC1 (0.68) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL20547202 | 0.90 | YTHDC1 (0.65) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL1501479 | 0.90 | NPC1 (0.73) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL29659561 | 0.90 | NPC1 (0.73) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL29659669 | 0.90 | YTHDC1 (0.64) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL5763160 | 0.90 | YTHDC1 (0.64) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL30410510 | 0.89 | NPC1 (0.60) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL20547443 | 0.88 | YTHDC1 (0.62) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL29659511 | 0.88 | YTHDC1 (0.62) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL20547488 | 0.87 | YTHDC1 (0.60) | YTHDC1NPC1RAB9ASMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615535-B1 | 9-(2-OXACYCLOALKYL)-9H-PURINE-2,6-DIAMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SKIN DISORDERS | UNIV PALACKEHO (CZ) | 2022-06-15 | — | — | EP | disclosed |