Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 0.76 |
| ▸ | BCL2 | P10415 | 3/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911288 | 0.87 | MCL1 (0.57) | MCL1ACP1BTKPIM3MAPT | |
| SCHEMBL1111184 | 0.83 | MCL1 (0.64) | MCL1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29660321 | 0.82 | MCL1 (0.52) | MCL1ACP1MAPTDYRK1AADORA3 | |
| SCHEMBL29911111 | 0.81 | MCL1 (0.51) | MCL1ACP1BTKPIM3MAPT | |
| SCHEMBL3131606 | 0.80 | MCL1 (0.65) | MCL1 | |
| SCHEMBL22939976 | 0.80 | MCL1 (0.50) | MCL1ACP1KMT2ABTKALDH1A1 | |
| SCHEMBL29911275 | 0.80 | MCL1 (0.50) | MCL1ACP1KMT2ABTKALDH1A1 | |
| SCHEMBL11154424 | 0.80 | MCL1 (0.55) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL11149772 | 0.77 | ALDH1A1 (0.57) | MCL1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11155810 | 0.77 | MCL1 (0.63) | MCL1KMT2AALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | disclosed |