SCHEMBL2966044

SCHEMBL2966044

COCOc1cc(C(=O)OC)ccc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.55
EGFR P00533 1/20 0.51
ALDH1A1 P00352 4/20 0.49
MAPT P10636 6/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 2/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
XDH P47989 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
CYP2C9 P11712 2/20 0.43
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1630042 0.88 HSD17B2 (0.57) MAPTLMNAGAACA12CA1
SCHEMBL17129602 0.86 L3MBTL1 (0.57) NOTUMALDH1A1MAPTTDP1L3MBTL1
SCHEMBL6155851 0.85 KMT2A (0.46) EGFRALDH1A1MAPTL3MBTL1LMNA
SCHEMBL1629306 0.85 EGFR (0.52) EGFRALDH1A1TDP1LMNAGAA
SCHEMBL10958234 0.85 NOTUM (0.56) NOTUMALDH1A1MAPTTDP1L3MBTL1
SCHEMBL2934574 0.84 TDP1 (0.52) NOTUMALDH1A1MAPTTDP1L3MBTL1
SCHEMBL18456830 0.84 MAPT (0.64) EGFRALDH1A1MAPTLMNACA12
SCHEMBL17991551 0.83 TDP1 (0.54) NOTUMALDH1A1MAPTTDP1L3MBTL1
SCHEMBL20602048 0.83 MAPT (0.53) EGFRALDH1A1MAPTL3MBTL1LMNA
SCHEMBL22324058 0.83 EGFR (0.50) NOTUMEGFRALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed