Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199224 | 1.00 | ADORA2A (0.32) | ADORA2AADORA1PTGS2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL23302365 | 0.88 | PLAU (0.34) | — | |
| SCHEMBL27199222 | 0.86 | IDH1 (0.38) | TGFBR1MEN1KMT2A | |
| SCHEMBL29660508 | 0.86 | IDH1 (0.38) | TGFBR1MEN1KMT2A | |
| SCHEMBL29660483 | 0.78 | SYK (0.38) | ADORA2AADORA1NPC1RAB9AKMT2A | |
| SCHEMBL23334273 | 0.78 | SYK (0.38) | ADORA2AADORA1NPC1RAB9AKMT2A | |
| SCHEMBL29660533 | 0.78 | RECQL (0.38) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27199215 | 0.78 | RECQL (0.38) | PTGS2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22042759 | 0.72 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30151244 | 0.72 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435076-B2 | Fluorine-containing pyrimidine compound and method for producing same | UNIMATEC CO., LTD. (JP) | 2025-10-07 | — | — | US | disclosed |
| CN-114502551-B | Fluorine-containing pyrimidine compound and preparation method thereof | 优迈特株式会社 | 2023-08-22 | — | — | CN | disclosed |
| EP-4053123-A1 | FLUORINATED PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING SAME | Unimatec Co., Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-114502551-A | Fluorine-containing pyrimidine compound and preparation method thereof | 优迈特株式会社 | 2022-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435076-B2 | Fluorine-containing pyrimidine compound and method for producing same | CNOT1, HAO1, NUDT1 | ADORA2A 538/4885ADORA1 108/4885PTGS2 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.