Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26965747 | 1.00 | MAPK1 (0.38) | MAPK1AXLHTR1AHTR7HTR6 | |
| SCHEMBL20575800 | 0.81 | DAO (0.41) | MAPK1AXL | |
| SCHEMBL21632480 | 0.81 | MAPK1 (0.36) | MAPK1AXLHTR1AHTR7HTR6 | |
| SCHEMBL30321255 | 0.81 | DAO (0.41) | MAPK1AXL | |
| SCHEMBL1468379 | 0.77 | GSK3B (0.37) | — | |
| SCHEMBL21632471 | 0.73 | AXL (0.47) | MAPK1AXL | |
| SCHEMBL29722097 | 0.73 | AXL (0.47) | MAPK1AXL | |
| SCHEMBL21632550 | 0.73 | AXL (0.41) | AXL | |
| SCHEMBL1564880 | 0.72 | DAO (0.35) | MAPK1AXL | |
| SCHEMBL24682764 | 0.70 | TRPA1 (0.38) | MAPK1AXLHTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247812-A1 | SUBSTITUTED PYRROLO [2, 3-B] PYRIDINE AND PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | Fochon Biosciences, Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |
| CN-116568686-A | Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors | 重庆复尚源创医药技术有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2022105746-A1 | SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2022-05-27 | — | — | WO | disclosed |