Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660886 | 0.86 | KDM4E (0.48) | MRGPRX1SMN1; SMN2NPSR1MEN1MAPT | |
| SCHEMBL29660685 | 0.83 | MAPT (0.50) | SMN1; SMN2PYGLNPSR1MEN1MAPT | |
| SCHEMBL29660728 | 0.76 | MAPT (0.53) | SMN1; SMN2PYGLMEN1MAPTHTT | |
| SCHEMBL20626114 | 0.73 | MRGPRX1 (0.49) | MRGPRX1SMN1; SMN2PYGLNPSR1MEN1 | |
| SCHEMBL25247535 | 0.71 | FFAR4 (0.56) | MRGPRX1SMN1; SMN2NPSR1MEN1MAPT | |
| SCHEMBL7345338 | 0.71 | ALDH1A1 (0.49) | MRGPRX1SMN1; SMN2NPSR1MEN1MAPT | |
| SCHEMBL10137052 | 0.69 | KMT2A (0.55) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL12264384 | 0.69 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL2547131 | 0.69 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL31563118 | 0.69 | MAPT (0.45) | SMN1; SMN2PYGLMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528802-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-01-20 | — | — | US | disclosed |
| US-20220274982-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-09-01 | — | — | US | disclosed |
| EP-4005638-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528802-B2 | Heterocyclic compound | GBA2, GBA1, GALC | MRGPRX1 1735/4885SMN1; SMN2 72/4885PYGL 2078/4885 |
| US-20220274982-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | MRGPRX1 2038/4885SMN1; SMN2 71/4885PYGL 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.