SCHEMBL29660819

SCHEMBL29660819

CO/C=C(/C(=O)OC)c1ccccc1Oc1cc(C(F)(F)F)ccn1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 3/20 0.41
HCRTR2 O43614 2/20 0.41
MAPK8 P45983 1/20 0.40
MAPK10 P53779 1/20 0.40
SORT1 Q99523 1/20 0.38
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
RORB Q92753 1/20 0.36
NCS1 P62166 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29013586 1.00 HCRTR1 (0.41) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL18291946 1.00 HCRTR1 (0.41) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL22511344 0.90 HCRTR1 (0.41) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL29393804 0.90 MEN1 (0.37) MAPK8MAPK10RXFP1MAPTMEN1
SCHEMBL203539 0.90 MEN1 (0.37) MAPK8MAPK10RXFP1MAPTMEN1
SCHEMBL18281652 0.90 HCRTR1 (0.39) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL18281651 0.90 HCRTR1 (0.39) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL24023024 0.90 MAPK8 (0.36) HCRTR1HCRTR2MAPK8MAPK10KDM4E
SCHEMBL22511318 0.88 HCRTR1 (0.40) HCRTR1HCRTR2MAPK8MAPK10SORT1
SCHEMBL24023065 0.86 MAPK8 (0.34) HCRTR1HCRTR2MAPK8MAPK10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330876-A Preparation method of Flupyroxystrobin 山东京博农化科技股份有限公司 2025-01-21 CN claimed
CN-119330876-A Preparation method of Flupyroxystrobin 山东京博农化科技股份有限公司 2025-01-21 CN disclosed
CN-119111556-A Insecticidal composition and application thereof 青岛滕润翔检测评价有限公司 2024-12-13 CN disclosed
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
US-11369113-B2 Vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2022-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 HCRTR1 1430/4885HCRTR2 2112/4885MAPK8 3810/4885
US-11369113-B2 Vector control compositions, methods and products utilizing same DDT, MSMO1, MGLL HCRTR1 2213/4885HCRTR2 2772/4885MAPK8 3527/4885
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same DDT, MLEC, MSMO1 HCRTR1 1430/4885HCRTR2 2112/4885MAPK8 3810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.