Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993092 | 1.00 | HTR2A (0.53) | HTR2ATAAR1HTR2C | |
| SCHEMBL16651484 | 0.92 | HTR2A (0.49) | HTR2ATAAR1HTR2C | |
| SCHEMBL3390504 | 0.86 | MTNR1A (0.44) | HTR2ATAAR1HTR2C | |
| SCHEMBL14659199 | 0.85 | HTR2A (0.44) | HTR2ATAAR1HTR2C | |
| SCHEMBL32690161 | 0.84 | HTR2A (0.56) | HTR2ATAAR1HTR2C | |
| SCHEMBL3989943 | 0.83 | HTR2A (0.51) | HTR2ATAAR1HTR2C | |
| SCHEMBL4293204 | 0.82 | HTR2A (0.47) | HTR2ATAAR1HTR2C | |
| SCHEMBL29836065 | 0.82 | HTR2A (0.47) | HTR2ATAAR1HTR2C | |
| SCHEMBL5307731 | 0.82 | HTR2A (0.65) | HTR2ATAAR1HTR2C | |
| SCHEMBL3775780 | 0.80 | HTR2A (0.41) | HTR2ATAAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-114616226-A | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2022-06-10 | — | — | CN | disclosed |
| EP-4003516-A1 | PYRIDINE DERIVATIVES AS TMEM16A MODULATORS FOR USE IN THE TREATMENT OF RESPIRATORY CONDITIONS | TMEM16A LIMITED (GB) | 2022-06-01 | — | — | EP | disclosed |