Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22918001 | 1.00 | CSNK2A1 (0.39) | CSNK2A1ESR1ESR2PTPN1ALOX15 | |
| SCHEMBL20095729 | 0.84 | CSNK2A1 (0.41) | CSNK2A1ESR1ESR2KDM1AKCNH2 | |
| SCHEMBL29749135 | 0.84 | CSNK2A1 (0.41) | CSNK2A1ESR1ESR2KDM1AKCNH2 | |
| SCHEMBL6903574 | 0.84 | ESR2 (0.40) | CSNK2A1ESR1ESR2ALOX15MEN1 | |
| SCHEMBL31053277 | 0.80 | CSNK2A1 (0.41) | CSNK2A1ESR1ESR2 | |
| SCHEMBL27176826 | 0.79 | CSNK2A1 (0.38) | CSNK2A1KDM1AKCNH2KDM1B | |
| SCHEMBL14810674 | 0.79 | CSNK2A1 (0.44) | CSNK2A1KDM1AKCNH2KDM1B | |
| SCHEMBL30408342 | 0.79 | CSNK2A1 (0.44) | CSNK2A1KDM1AKCNH2KDM1B | |
| SCHEMBL21259084 | 0.79 | ESR2 (0.39) | CSNK2A1ESR1ESR2ALOX15MEN1 | |
| SCHEMBL3366188 | 0.78 | CSNK2A1 (0.42) | CSNK2A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114616226-A | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2022-06-10 | — | — | CN | disclosed |
| EP-4003516-A1 | PYRIDINE DERIVATIVES AS TMEM16A MODULATORS FOR USE IN THE TREATMENT OF RESPIRATORY CONDITIONS | TMEM16A LIMITED (GB) | 2022-06-01 | — | — | EP | disclosed |