Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14810674 | 1.00 | CSNK2A1 (0.44) | CSNK2A1KDM1AKDM1BCYP2A6KCNH2 | |
| SCHEMBL24384654 | 0.93 | CSNK2A1 (0.44) | CSNK2A1KDM1AKDM1BCYP2A6 | |
| SCHEMBL3369370 | 0.85 | CSNK2A1 (0.44) | CSNK2A1KDM1AKDM1BCYP2A6KCNH2 | |
| SCHEMBL696046 | 0.82 | CSNK2A1 (0.37) | CSNK2A1KDM1AKDM1BCYP2A6KCNH2 | |
| SCHEMBL20095729 | 0.82 | CSNK2A1 (0.41) | CSNK2A1KDM1AKDM1BKCNH2 | |
| SCHEMBL29749135 | 0.82 | CSNK2A1 (0.41) | CSNK2A1KDM1AKDM1BKCNH2 | |
| SCHEMBL22918001 | 0.79 | CSNK2A1 (0.39) | CSNK2A1KDM1AKDM1BKCNH2 | |
| SCHEMBL29660946 | 0.79 | CSNK2A1 (0.39) | CSNK2A1KDM1AKDM1BKCNH2 | |
| SCHEMBL31053277 | 0.79 | CSNK2A1 (0.41) | CSNK2A1 | |
| SCHEMBL3365689 | 0.78 | CSNK2A1 (0.44) | CSNK2A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572755-A2 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024039901-A2 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |