Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 2/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804964 | 1.00 | CYSLTR1 (0.62) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL4432278 | 0.89 | MGLL (0.65) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL30207797 | 0.89 | MGLL (0.65) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL2746902 | 0.86 | MGLL (0.62) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL3694153 | 0.86 | POLB (0.68) | MGLLROCK2TP53MAPTNPC1 | |
| SCHEMBL6400257 | 0.85 | MGLL (0.72) | MGLLNPC1ALDH1A1RAB9APOLB | |
| SCHEMBL1530116 | 0.84 | MGLL (0.59) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL3580828 | 0.83 | CYSLTR1 (0.54) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL7404743 | 0.82 | MGLL (0.56) | CYSLTR1MGLLROCK2TP53MAPT | |
| SCHEMBL2328795 | 0.82 | MGLL (0.56) | MGLLROCK2TP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729331-A | Chemically modified adeno-associated virus | 法国国家科学研究中心 | 2022-07-08 | — | — | CN | disclosed |