Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591091 | 0.99 | TASP1 (0.46) | FOLH1MMETASP1DPP4DPP8 | |
| SCHEMBL31462056 | 0.97 | FOLH1 (0.47) | FOLH1MMETASP1DPP4DPP8 | |
| SCHEMBL29649110 | 0.95 | MME (0.49) | FOLH1MMETASP1DPP4DPP8 | |
| SCHEMBL30903465 | 0.93 | FOLH1 (0.49) | FOLH1DPP4DPP8DPP9NOD1 | |
| SCHEMBL4221701 | 0.93 | FOLH1 (0.51) | FOLH1MMEDPP4DPP8DPP9 | |
| SCHEMBL4221705 | 0.93 | FOLH1 (0.51) | FOLH1MMEDPP4DPP8DPP9 | |
| SCHEMBL31695399 | 0.92 | FOLH1 (0.51) | FOLH1TASP1DPP4DPP8DPP9 | |
| SCHEMBL30193496 | 0.90 | FOLH1 (0.56) | FOLH1MMEDPP4DPP8DPP9 | |
| SCHEMBL29381184 | 0.89 | DPP4 (0.50) | FOLH1MMETASP1DPP4DPP8 | |
| SCHEMBL30808892 | 0.89 | BACE1 (0.48) | FOLH1DPP4DPP8DPP9NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12214015-B2 | Use of c-type natriuretic peptide variants to treat osteoarthritis | BIOMARIN PHARMACEUTICAL INC. (US) | 2025-02-04 | — | — | US | disclosed |
| US-20220160836-A1 | USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS | BIOMARIN PHARMACEUTICAL INC. | 2022-05-26 | — | — | US | disclosed |