SCHEMBL29663974

SCHEMBL29663974

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccccc1)C(C)C)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 11/20 0.68
▸ GLP1R P43220 4/20 0.56
▸ OPRM1 P35372 1/20 0.54
▸ OPRD1 P41143 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661265 0.97 GRPR (0.65) GRPRGLP1ROPRM1OPRD1
SCHEMBL6510905 0.97 GRPR (0.68) GRPRGLP1ROPRM1OPRD1
SCHEMBL30118089 0.96 GRPR (0.65) GRPRGLP1ROPRM1OPRD1
SCHEMBL31069834 0.96 GRPR (0.66) GRPRGLP1R
SCHEMBL2193571 0.95 GRPR (0.67) GRPRGLP1ROPRM1OPRD1
SCHEMBL31223150 0.95 GRPR (0.61) GRPRGLP1ROPRM1OPRD1
SCHEMBL30816315 0.95 GRPR (0.63) GRPRGLP1R
SCHEMBL30628977 0.95 GRPR (0.64) GRPRGLP1R
SCHEMBL30628996 0.94 GRPR (0.62) GRPRGLP1R
SCHEMBL38661925 0.94 GRPR (0.61) GRPRGLP1ROPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098519-A1 RADIOLIGAND COMPOUNDS AND USES THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-05-15 — — WO disclosed
US-20250332301-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION NOVARTIS AG (CH) 2025-10-30 — — US disclosed
CN-120081907-A Radiolabeled bombesin derivative compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2025-06-03 — — CN disclosed
CN-119868594-A Method for radiolabelling GRPR antagonist and kit thereof 诺华股份有限公司 2025-04-25 — — CN disclosed
CN-114728087-B Method for radiolabelling GRPR antagonist and kit thereof 诺华股份有限公司 2025-02-07 — — CN disclosed
US-20220401593-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION NOVARTIS AG (CH) 2022-12-22 — — US disclosed
US-20220378954-A1 METHODS FOR RADIOLABELLING GRPR ANTAGONISTS AND THEIR KITS NOVARTIS AG (CH) 2022-12-01 — — US disclosed
EP-4031193-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION Novartis AG (CH) 2022-07-27 — — EP disclosed
EP-4031194-A1 METHODS FOR RADIOLABELLING GRPR ANTAGONISTS AND THEIR KITS Novartis AG (CH) 2022-07-27 — — EP disclosed
CN-114728087-A Method for radiolabeling GRPR antagonist and kit thereof 诺华股份有限公司 2022-07-08 — — CN disclosed
CN-114728088-A Stable concentrated radiopharmaceutical compositions 诺华股份有限公司 2022-07-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332301-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION RAB5IF, TMEM14C, PAICS GRPR 1170/4885GLP1R 2897/4885OPRM1 1823/4885
US-20220378954-A1 METHODS FOR RADIOLABELLING GRPR ANTAGONISTS AND THEIR KITS GRPR, CCKBR, GIPR GRPR 1/4885GLP1R 18/4885OPRM1 723/4885
US-20220401593-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION RAB5IF, TMEM14C, PAICS GRPR 1170/4885GLP1R 2897/4885OPRM1 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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