Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.51 |
| ▸ | PDE4A | P27815 | 11/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.51 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17112499 | 1.00 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CATXN2 | |
| SCHEMBL17112486 | 0.86 | PDE4D (0.54) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2543514 | 0.84 | KMT2A (0.51) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL12800157 | 0.84 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2586121 | 0.83 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL17112462 | 0.83 | ATXN2 (0.59) | PDE4DPDE4APDE4BPDE4CATXN2 | |
| SCHEMBL7360996 | 0.83 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7359837 | 0.83 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL17908087 | 0.83 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7361406 | 0.83 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204550-B | Bicyclic compounds as Autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors | 豪夫迈·罗氏有限公司 | 2022-05-17 | — | — | CN | disclosed |