Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047119 | 1.00 | GAA (0.39) | GAACFTRALDH1A1KMT2ASIRT6 | |
| SCHEMBL29047116 | 0.84 | TLR8 (0.41) | GAAALDH1A1MAPTMCHR2MCHR1 | |
| SCHEMBL7406275 | 0.72 | TDP1 (0.47) | ALDH1A1KMT2ASIRT6MAPTMEN1 | |
| SCHEMBL21248533 | 0.70 | CYP1A2 (0.46) | GAAKMT2ALMNAMEN1NPC1 | |
| SCHEMBL29262067 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL4677098 | 0.69 | TDP1 (0.49) | ALDH1A1KMT2ASIRT6MAPTMEN1 | |
| SCHEMBL20660870 | 0.69 | FLT1 (0.40) | GAAKMT2ALMNAMEN1 | |
| SCHEMBL1876592 | 0.69 | GAA (0.56) | GAAALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL14052805 | 0.68 | GAA (0.55) | GAACFTRALDH1A1LMNA | |
| SCHEMBL29664247 | 0.68 | KDM4E (0.47) | GAAALDH1A1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022121813-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2022-06-16 | — | — | WO | disclosed |