Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.62 |
| ▸ | QDPR | P09417 | 1/20 | 0.59 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366769 | 1.00 | HTR2C (0.62) | HTR2CQDPRSLC18A3SIGMAR1DRD2 | |
| SCHEMBL7405883 | 0.89 | DRD2 (0.55) | HTR2CQDPRDRD2DRD3 | |
| SCHEMBL29427014 | 0.86 | DRD2 (0.59) | SIGMAR1DRD2DRD3 | |
| SCHEMBL1608042 | 0.86 | DRD2 (0.59) | SIGMAR1DRD2DRD3 | |
| Tert-Butyl Formate SCHEMBL27487857 | 0.83 | HTR2C (0.49) | HTR2CQDPRSLC18A3SIGMAR1DRD2 | |
| SCHEMBL1661863 | 0.82 | HDAC4 (0.61) | SIGMAR1DRD2DRD3 | |
| SCHEMBL1658753 | 0.82 | HDAC4 (0.56) | SIGMAR1DRD2DRD3 | |
| SCHEMBL566627 | 0.80 | DRD2 (0.62) | SIGMAR1DRD2DRD3 | |
| SCHEMBL3037442 | 0.80 | DRD2 (0.62) | SIGMAR1DRD2DRD3 | |
| SCHEMBL3356779 | 0.80 | HDAC4 (0.59) | SIGMAR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728939-B | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728939-A | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2022-07-08 | — | — | CN | disclosed |