Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.60 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273889 | 1.00 | CYP2C9 (0.60) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7408943 | 0.91 | CYP2C9 (0.73) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7267980 | 0.90 | PYGL (0.61) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL7275341 | 0.90 | CYP2C9 (0.59) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| Imidazole SCHEMBL8912931 | 0.89 | CYP2C9 (0.49) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL29808895 | 0.87 | TSHR (0.62) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL2563899 | 0.87 | TSHR (0.62) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL820019 | 0.86 | KDM4E (0.78) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL30872863 | 0.86 | KDM4E (0.78) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL29663663 | 0.86 | KDM4E (0.78) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114569581-A | Felodipine sustained-release capsule and preparation method thereof | 江苏联环药业股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110128249-B | Synthetic method of felodipine intermediate 2, 3-dichlorobenzaldehyde | 深圳市第二人民医院 | 2022-04-01 | — | — | CN | disclosed |