SCHEMBL29664646

SCHEMBL29664646

CCCOC(=O)c1ccc(N)cc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2D6 P10635 1/20 0.56
SCN1A P35498 1/20 0.56
SCN2A Q99250 1/20 0.56
SCN3A Q9NY46 1/20 0.56
HSD17B10 Q99714 5/20 0.54
CHRM2 P08172 1/20 0.52
CHRM3 P20309 1/20 0.52
MAOA P21397 1/20 0.52
HTR2C P28335 1/20 0.52
CHRNA4 P43681 1/20 0.52
HTR3A P46098 1/20 0.52
KCNH2 Q12809 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
KDM4E B2RXH2 6/20 0.51
POLB P06746 3/20 0.51
TSHR P16473 4/20 0.49
LMNA P02545 2/20 0.49
CYP3A4 P08684 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2133553 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL29649166 0.94 CYP1A2 (0.51) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL11109738 0.90 ALDH1A1 (0.68) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL12774710 0.88 ALDH1A1 (0.69) ALDH1A1CYP1A2HSD17B10KDM4EPOLB
SCHEMBL6362627 0.88 ALDH1A1 (0.69) ALDH1A1CYP1A2HSD17B10KDM4EPOLB
SCHEMBL6362319 0.88 ALDH1A1 (0.69) ALDH1A1CYP1A2HSD17B10KDM4EPOLB
SCHEMBL13124103 0.88 ALDH1A1 (0.69) ALDH1A1CYP1A2HSD17B10KDM4EPOLB
SCHEMBL29204388 0.87 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL29375324 0.86 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL2132644 0.86 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP2D6SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776942-A Method for preparing diaminobenzoic acid based on dinitrobenzoic acid 清源创新实验室 2024-03-29 CN disclosed
CN-114507149-A Diamine compound, polymer, alignment agent, alignment film, and liquid crystal display element 奇美实业股份有限公司 2022-05-17 CN disclosed