Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812447 | 1.00 | MAPT (0.58) | MAPTGAAMAPK14AKR1C3ALDH1A1 | |
| Benzenesulfonamide SCHEMBL3088171 | 0.88 | CA1 (0.52) | MAPTGAAMAPK14 | |
| SCHEMBL30549383 | 0.85 | MAPT (0.53) | MAPTGAAMAPK14AKR1C3ALDH1A1 | |
| SCHEMBL15619489 | 0.84 | AKR1C3 (0.53) | MAPTGAAAKR1C3ALDH1A1LMNA | |
| SCHEMBL15628232 | 0.84 | PARP1 (0.53) | MAPTGAAMAPK14LMNAMEN1 | |
| SCHEMBL29433447 | 0.82 | AKR1C3 (0.61) | MAPTGAAMAPK14AKR1C3ALDH1A1 | |
| SCHEMBL333008 | 0.82 | AKR1C3 (0.61) | MAPTGAAMAPK14AKR1C3ALDH1A1 | |
| SCHEMBL15628212 | 0.82 | ALDH1A1 (0.55) | MAPK14ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15628169 | 0.82 | POLB (0.58) | MAPTMAPK14ALDH1A1KMT2APOLB | |
| Methylamine SCHEMBL10828909 | 0.81 | GAA (0.57) | MAPTGAAMAPK14AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |