Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394720 | 1.00 | KDM4C (0.47) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL28509680 | 0.98 | KDM4C (0.49) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL29575095 | 0.84 | SMN1; SMN2 (0.47) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL18395417 | 0.84 | SMN1; SMN2 (0.47) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL4309528 | 0.83 | CDC7 (0.62) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL15286530 | 0.83 | CA12 (0.55) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL5800319 | 0.80 | MAPT (0.56) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL15286333 | 0.78 | KDM4E (0.47) | KDM4CKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL3627591 | 0.75 | NPC1 (0.61) | KDM4EMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL227731 | 0.75 | NPC1 (0.71) | KDM4EALDH1A1L3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |