Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23216915 | 1.00 | MAPT (0.44) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL827601 | 0.80 | MAPT (0.52) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL28781305 | 0.80 | MEN1 (0.48) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL23232151 | 0.80 | NSD2 (0.43) | MAPTKDM4ELMNAHTTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11973872 | 0.79 | MAPT (0.50) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL28781316 | 0.77 | MAPT (0.38) | MAPTKDM4ELMNAHTTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23215044 | 0.77 | NSD2 (0.40) | KDM4ELMNAHTTALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29664501 | 0.77 | NSD2 (0.40) | KDM4ELMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL23215101 | 0.74 | SSTR4 (0.41) | MAPTKDM4ELMNAHTTALDH1A1 | |
| SCHEMBL23215045 | 0.74 | ALDH1A1 (0.37) | MAPTLMNAHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |