Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709792 | 1.00 | NOTUM (0.52) | NOTUMKDM4ELMNANPC1RAB9A | |
| SCHEMBL3042222 | 0.82 | CHEK1 (0.49) | NOTUMKDM4ELMNANPC1RAB9A | |
| SCHEMBL6524542 | 0.82 | IDO1 (0.50) | NOTUMKDM4ELMNANPC1RAB9A | |
| SCHEMBL30693692 | 0.81 | NOTUM (0.56) | NOTUMBTKGAANPY5R | |
| SCHEMBL8515018 | 0.79 | NOTUM (0.54) | NOTUMKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL1456454 | 0.79 | KDM4E (0.62) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29624537 | 0.79 | KDM4E (0.62) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20510086 | 0.78 | KDM4E (0.50) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1456955 | 0.77 | KDM4E (0.59) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7062776 | 0.77 | KDM4E (0.48) | KDM4ELMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125736-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-16 | — | — | WO | disclosed |