SCHEMBL7062776

SCHEMBL7062776

N=c1cccc(-c2ccccn2)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.48
LMNA P02545 5/20 0.48
METAP1 P53582 4/20 0.48
CCR1 P32246 2/20 0.48
CCR5 P51681 2/20 0.48
CCR8 P51685 2/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
SMN1; SMN2 Q16637 5/20 0.47
TP53 P04637 3/20 0.47
ALOX15 P16050 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
HTT P42858 2/20 0.47
ALPL P05186 2/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624537 0.79 KDM4E (0.62) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL1456454 0.79 KDM4E (0.62) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL1456955 0.77 KDM4E (0.59) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL5709792 0.77 NOTUM (0.52) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL29664837 0.77 NOTUM (0.52) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL3751172 0.76 KDM4E (0.61) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL3745096 0.74 KDM4E (0.65) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL31140230 0.73 NPY5R (0.50) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL20595286 0.73 NPY5R (0.50) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL20510086 0.71 KDM4E (0.50) KDM4ELMNAMETAP1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183279-B1 POLYMERIZATION OF ETHYLENE DU PONT (US) 2004-11-24 EP disclosed
EP-1183279-B1 POLYMERIZATION OF ETHYLENE DU PONT (US) 2004-11-24 EP disclosed
US-6417364-B1 NICKEL OR IRON COMPLEXES OF SELECTED NOVEL 2,2-BIPYRIDINE-6-IMINES, OPTIONALLY WITH THE ADDITION OF OTHER COCATALYSTS. THE POLYMERS ARE USEFUL FOR FILMS AND MOLDING RESINS. E. I. DU PONT DE NEMOURS AND COMPANY 2002-07-09 US disclosed
US-6417364-B1 NICKEL OR IRON COMPLEXES OF SELECTED NOVEL 2,2-BIPYRIDINE-6-IMINES, OPTIONALLY WITH THE ADDITION OF OTHER COCATALYSTS. THE POLYMERS ARE USEFUL FOR FILMS AND MOLDING RESINS. E. I. DU PONT DE NEMOURS AND COMPANY 2002-07-09 US disclosed
US-20020061987-A1 Polymerization of ethylene LENGES GERALDINE MARIE (US) 2002-05-23 US disclosed
US-20020061987-A1 Polymerization of ethylene LENGES GERALDINE MARIE (US) 2002-05-23 US disclosed
US-6365690-B1 CATALYTIC OLEFIN POLYMERIZATION WITH NICKEL IRON COMPLEXES WITH BIPYRIDINE LIGANDS E. I. DU PONT DE NEMOURS AND COMPANY 2002-04-02 US disclosed
US-6365690-B1 CATALYTIC OLEFIN POLYMERIZATION WITH NICKEL IRON COMPLEXES WITH BIPYRIDINE LIGANDS E. I. DU PONT DE NEMOURS AND COMPANY 2002-04-02 US disclosed
EP-1183279-A1 POLYMERIZATION OF ETHYLENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-03-06 EP disclosed
WO-2000068280-A1 POLYMERIZATION OF ETHYLENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-16 WO disclosed