Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.62 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL29664050 | 0.84 | SLC7A5 (0.83) | ESR1ESR2SLC7A5GRB2PTPN1 | |
| Tyrosine SCHEMBL7445681 | 0.84 | SLC7A5 (0.83) | ESR1ESR2SLC7A5GRB2PTPN1 | |
| SCHEMBL32671739 | 0.84 | ALPI (0.63) | SLC7A5GRB2HDAC8PTPN1 | |
| Trifluoroacetic Acid SCHEMBL5302813 | 0.83 | SLC7A5 (0.64) | ESR1ESR2SLC7A5GRB2TAAR1 | |
| Trifluoroacetic Acid SCHEMBL5987000 | 0.83 | SLC7A5 (0.64) | ESR1ESR2SLC7A5GRB2TAAR1 | |
| Hydrochloric Acid SCHEMBL8195630 | 0.82 | ALPI (0.61) | SLC7A5GRB2HDAC8PTPN1 | |
| SCHEMBL16501755 | 0.82 | SLC7A5 (0.62) | ESR1ESR2SLC7A5TAAR1SLC6A2 | |
| SCHEMBL13301968 | 0.82 | SLC7A5 (0.62) | ESR1ESR2SLC7A5TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8200680 | 0.82 | ALPI (0.61) | SLC7A5GRB2HDAC8PTPN1 | |
| SCHEMBL28523750 | 0.79 | SLC7A5 (0.69) | ESR1ESR2SLC7A5GRB2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160905-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160905-A1 | FLUORINATION METHOD | AFF2, AFF1, AFF4 | ESR1 2724/4885ESR2 2562/4885SLC7A5 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.