SCHEMBL29664935

SCHEMBL29664935

Nc1ccn([C@@H]2OC(COP(=O)(O)OP(=O)(O)O)=C[C@H]2O)c(=O)n1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.51
P2RY2 P41231 8/20 0.48
POLB P06746 1/20 0.46
P2RY6 Q15077 9/20 0.45
P2RY4 P51582 5/20 0.45
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.43
MTOR P42345 1/20 0.43
MDM2 Q00987 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678646 0.98 POLG (0.54) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL20766759 0.98 POLG (0.54) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL22678647 0.98 POLG (0.54) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL24512478 0.92 LMNA (0.46) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL24782133 0.92 LMNA (0.46) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL29664879 0.86 NT5E (0.50) P2RY2POLBLMNATHRBMTOR
SCHEMBL29664912 0.83 POLG (0.45) POLGP2RY2POLBP2RY6P2RY4
SCHEMBL29664852 0.82 POLG (0.48) POLGP2RY2POLBP2RY6P2RY4
Phosphoric Acid SCHEMBL20766989 0.82 LMNA (0.52) POLGP2RY2POLBLMNATHRB
SCHEMBL24781261 0.79 LMNA (0.46) P2RY2LMNATHRBMTORMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022123501-A1 PROTECTED DEOXYDIDEHYDRO-NUCLEOSIDES VICTORIA LINK LIMITED (NZ) 2022-06-16 WO disclosed