Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18587546 | 1.00 | YTHDC1 (0.60) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29665011 | 0.90 | YTHDC1 (0.58) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL18587088 | 0.90 | YTHDC1 (0.61) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL18587097 | 0.90 | YTHDC1 (0.58) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29664971 | 0.90 | YTHDC1 (0.61) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL18587104 | 0.87 | NPC1 (0.64) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29664963 | 0.87 | NPC1 (0.64) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29664961 | 0.85 | YTHDC1 (0.59) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL18587965 | 0.85 | YTHDC1 (0.59) | YTHDC1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL20547426 | 0.84 | NPC1 (0.68) | YTHDC1NPC1RAB9ASMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | claimed |