Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009700 | 0.84 | BLM (0.51) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL28395639 | 0.83 | ALDH1A1 (0.41) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL2034707 | 0.82 | CTBP2 (0.47) | ALDH1A1HPGDGAAKMT2AKDM4E | |
| SCHEMBL2032866 | 0.82 | CTBP2 (0.47) | ALDH1A1HPGDGAAKMT2AKDM4E | |
| SCHEMBL11877078 | 0.82 | BLM (0.54) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL4458475 | 0.81 | KDM4E (0.51) | ALDH1A1HPGDGAAKMT2AKDM4E | |
| SCHEMBL427854 | 0.81 | BLM (0.49) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL28690512 | 0.81 | BLM (0.49) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL427855 | 0.81 | BLM (0.49) | BLMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL29521900 | 0.81 | BLM (0.49) | BLMALDH1A1HPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178366-A1 | GLP-1R, GIP-R AND/OR GCGR AGONISTS, FORMULATIONS, AND METHODS OF USE | SPITFIRE PHARMA LLC (US) | 2022-08-25 | — | — | WO | disclosed |