Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666629 | 0.92 | HCRTR2 (0.48) | HCRTR2 | |
| SCHEMBL23391530 | 0.83 | HCRTR2 (0.39) | HCRTR2 | |
| SCHEMBL31034884 | 0.82 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL23391502 | 0.80 | HCRTR2 (0.43) | HCRTR2 | |
| SCHEMBL29714596 | 0.80 | HCRTR2 (0.43) | HCRTR2 | |
| SCHEMBL29666709 | 0.79 | HCRTR2 (0.70) | HCRTR2 | |
| SCHEMBL29666638 | 0.79 | HCRTR2 (0.61) | HCRTR2 | |
| SCHEMBL12821615 | 0.77 | GPR119 (0.54) | — | |
| SCHEMBL26185985 | 0.77 | HCRTR2 (0.52) | HCRTR2 | |
| SCHEMBL29666668 | 0.75 | HCRTR2 (0.47) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247801-A1 | 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109117-A1 | 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |