Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.56 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666836 | 0.95 | HDAC4 (0.57) | ITGAVITGB3ITGA5ITGB1ITGB5 | |
| SCHEMBL29666771 | 0.93 | ERBB2 (0.57) | ITGAVITGB3ITGA5ITGB1ITGB5 | |
| SCHEMBL30037692 | 0.92 | ITGAV (0.60) | ITGAVITGB3ITGA5ITGB1ITGB5 | |
| SCHEMBL29666536 | 0.92 | HDAC4 (0.54) | ITGAVITGB3ITGA5ITGB1ITGB5 | |
| SCHEMBL29666863 | 0.91 | HDAC4 (0.56) | ITGAVITGB3ITGA5ITGB1ITGB5 | |
| SCHEMBL29666795 | 0.91 | KRAS (0.56) | KRASERBB2HDAC4HDAC1HDAC3 | |
| SCHEMBL29666774 | 0.91 | HDAC4 (0.60) | KRASERBB2HDAC4HDAC1HDAC3 | |
| SCHEMBL29666804 | 0.91 | HDAC4 (0.60) | KRASERBB2HDAC4HDAC1HDAC3 | |
| SCHEMBL29666794 | 0.91 | HDAC4 (0.60) | KRASERBB2HDAC4HDAC1HDAC3 | |
| SCHEMBL29666732 | 0.91 | HDAC4 (0.60) | KRASERBB2HDAC4HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | ITGAV 3880/4885ITGB3 3724/4885ITGA5 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.