Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666740 | 1.00 | ACE (0.58) | ACEACE2OPRK1XIAP | |
| SCHEMBL29666711 | 0.94 | ACE (0.59) | ACEACE2OPRK1 | |
| SCHEMBL29666748 | 0.93 | ACE (0.57) | ACEACE2OPRK1 | |
| SCHEMBL29666840 | 0.93 | ACE (0.58) | ACEACE2XIAP | |
| SCHEMBL29666769 | 0.93 | ACE (0.58) | ACEACE2XIAP | |
| SCHEMBL29666860 | 0.92 | ACE (0.57) | ACEACE2OPRK1XIAP | |
| SCHEMBL29666773 | 0.92 | ACE (0.59) | ACEACE2XIAP | |
| SCHEMBL29666707 | 0.91 | ACE (0.60) | ACEACE2XIAP | |
| SCHEMBL29666745 | 0.91 | ACE (0.58) | ACEACE2XIAP | |
| SCHEMBL29666817 | 0.90 | ACE (0.58) | ACEACE2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | ACE 900/4885ACE2 1876/4885OPRK1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.