Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666871 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666806 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666702 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666923 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666796 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666755 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666763 | 0.93 | MAPK8 (0.62) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666756 | 0.93 | MAPK8 (0.61) | MAPK8MAPK9MAPK10KDM1AEPHA2 | |
| SCHEMBL29666837 | 0.91 | MAPK8 (0.61) | MAPK8MAPK9MAPK10CALCRLKDM1A | |
| SCHEMBL29666742 | 0.90 | MAPK8 (0.66) | MAPK8MAPK9MAPK10KDM1AEPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | MAPK8 2980/4885MAPK9 2784/4885MAPK10 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.