Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666780 | 0.97 | MAPK8 (0.58) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666767 | 0.97 | MAPK8 (0.58) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666809 | 0.96 | MAPK8 (0.57) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666718 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666766 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666846 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666921 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666781 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666749 | 0.95 | MAPK8 (0.59) | MAPK8MAPK9MAPK10EPHA2OPRM1 | |
| SCHEMBL29666694 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10EPHA2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | MAPK8 2980/4885MAPK9 2784/4885MAPK10 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.