SCHEMBL29668447

SCHEMBL29668447

O=S(=O)(O)c1ccc2cc(Nc3ccccc3)ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 1.00
CASP6 P55212 2/20 0.73
NSD2 O96028 1/20 0.73
DUSP3 P51452 1/20 0.73
PTPN5 P54829 1/20 0.73
CASP7 P55210 1/20 0.73
PTPN11 Q06124 1/20 0.73
ALDH1A1 P00352 4/20 0.61
HSD17B10 Q99714 3/20 0.61
CYP3A4 P08684 1/20 0.61
HPGD P15428 1/20 0.61
TNNI3 P19429 1/20 0.50
TNNT2 P45379 1/20 0.50
TNNC1 P63316 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
PTPRA P18433 1/20 0.47
PTPRB P23467 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843770 1.00 SNCA (1.00) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL278412 1.00 SNCA (1.00) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL2129185 0.95 SNCA (0.90) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL4349757 0.91 SNCA (0.83) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL11674227 0.90 SNCA (0.81) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL11742527 0.87 SNCA (0.77) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL9717494 0.86 SNCA (0.76) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL315795 0.85 SNCA (0.73) SNCACASP6NSD2DUSP3PTPN5
SCHEMBL9479439 0.85 SNCA (0.73) SNCACASP6NSD2DUSP3PTPN5
Succinic Acid SCHEMBL28747359 0.85 SNCA (0.72) SNCACASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114634428-B Microwave condition preparation method of 6-anilino/p-toluidinyl-2-naphthalene sulfonic acid 仁景(苏州)生物科技有限公司 2024-05-10 CN disclosed
US-11921117-B2 Characterization of subvisible particles using a particle analyzer TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-03-05 US disclosed
EP-4063854-A1 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER Takeda Pharmaceutical Company Limited (JP) 2022-09-28 EP disclosed
EP-2802871-B1 CHARACTERIZATION OF SUBVISIBLE PARTICLES USING A PARTICLE ANALYZER TAKEDA PHARMACEUTICALS CO (JP) 2022-07-27 EP disclosed
CN-114634428-A Microwave condition preparation method of 6-anilino/p-toluidino-2-naphthalenesulfonic acid 仁景(苏州)生物科技有限公司 2022-06-17 CN disclosed