Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238646 | 1.00 | POLB (0.38) | POLBSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL20252644 | 0.94 | SMN1; SMN2 (0.33) | POLBSMN1; SMN2TSHRALOX15ALDH1A1 | |
| SCHEMBL15464432 | 0.92 | POLB (0.39) | POLBSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL15463758 | 0.91 | POLB (0.39) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL29669041 | 0.90 | POLB (0.37) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL20238577 | 0.90 | POLB (0.37) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL14934588 | 0.89 | POLB (0.41) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL29481979 | 0.89 | POLB (0.41) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL20095731 | 0.89 | POLB (0.37) | POLBMEN1KMT2ATSHRCYP1A2 | |
| SCHEMBL19613950 | 0.86 | OXTR (0.37) | SMN1; SMN2MEN1KMT2ATSHRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |