Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 6/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237767 | 1.00 | SCN1A (0.44) | SCN1ASCN5ASCN8ACYP2A13PDCD1 | |
| SCHEMBL29668886 | 0.86 | SCN1A (0.44) | SCN1ASCN5ASCN8ACYP2A13PDCD1 | |
| SCHEMBL20237436 | 0.86 | SCN1A (0.44) | SCN1ASCN5ASCN8ACYP2A13PDCD1 | |
| SCHEMBL20256843 | 0.83 | PDCD1LG2 (0.44) | SCN1ASCN5ASCN8ACYP2A13CD274 | |
| SCHEMBL20238852 | 0.79 | SCN1A (0.42) | SCN1ASCN5ASCN8ACYP2A13PDCD1 | |
| SCHEMBL29668750 | 0.79 | SCN1A (0.42) | SCN1ASCN5ASCN8ACYP2A13PDCD1 | |
| SCHEMBL20256954 | 0.78 | CYP2A13 (0.69) | CYP2A13KDM4EALDH1A1POLBOPRM1 | |
| SCHEMBL20238193 | 0.76 | KDM4E (0.58) | CYP2A13KDM4EALDH1A1POLBSIGMAR1 | |
| SCHEMBL29668956 | 0.76 | KDM4E (0.58) | CYP2A13KDM4EALDH1A1POLBSIGMAR1 | |
| SCHEMBL20238623 | 0.74 | RORC (0.48) | PDCD1CD274GHSRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |