Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856167 | 0.86 | TP53 (0.69) | TP53ALDH1A1GAAMAPK1MAPT | |
| SCHEMBL28279207 | 0.86 | TP53 (0.67) | TP53ALDH1A1GAAKMT2AMAPK1 | |
| SCHEMBL20248078 | 0.84 | TP53 (0.57) | TP53PGRALDH1A1GAAKMT2A | |
| SCHEMBL20242215 | 0.83 | TP53 (0.56) | TP53PGRALDH1A1GAAKMT2A | |
| SCHEMBL12494308 | 0.82 | SMN1; SMN2 (0.66) | TP53ALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL15464777 | 0.81 | TP53 (0.62) | TP53ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28211731 | 0.81 | MEN1 (0.63) | TP53PGRALDH1A1GAAKMT2A | |
| SCHEMBL2856162 | 0.81 | TP53 (0.59) | TP53ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL29250014 | 0.81 | TP53 (0.67) | TP53GAAPKMSMN1; SMN2LMNA | |
| SCHEMBL12982388 | 0.79 | TP53 (0.68) | TP53ALDH1A1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |