Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238064 | 1.00 | TDP1 (0.41) | TDP1POLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28740317 | 0.93 | KMT2A (0.41) | TDP1POLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20252703 | 0.90 | TP53 (0.39) | TDP1POLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20238176 | 0.90 | KDM4E (0.39) | TDP1POLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL15466255 | 0.87 | POLB (0.40) | TDP1POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL29668985 | 0.87 | GAA (0.40) | TDP1POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL14921470 | 0.87 | ALDH1A1 (0.40) | TDP1POLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20238105 | 0.87 | GAA (0.40) | TDP1POLBALDH1A1KDM4EMEN1 | |
| SCHEMBL20238565 | 0.86 | KMT2A (0.37) | POLBALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29669086 | 0.86 | KMT2A (0.37) | POLBALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |