Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.41 |
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237959 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL21777833 | 0.96 | ALDH1A1 (0.49) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL29669033 | 0.88 | CYP2A13 (0.48) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL20238899 | 0.88 | CYP2A13 (0.48) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL20238516 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL29669155 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL20238493 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EPRMT6 | |
| SCHEMBL29669110 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EPRMT6 | |
| SCHEMBL20238341 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4EPRMT6 | |
| Methylamine SCHEMBL20238761 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4EPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |