Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 5/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320432 | 1.00 | TRPV4 (0.41) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL29669007 | 1.00 | TRPV4 (0.41) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL30485974 | 0.91 | TRPV4 (0.41) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL1501202 | 0.91 | TRPV4 (0.41) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL1829297 | 0.88 | TRPV4 (0.42) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL29503458 | 0.88 | TRPV4 (0.42) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL3948181 | 0.86 | TRPV4 (0.46) | TRPV4CA1CA2CA9PTGES2 | |
| SCHEMBL320605 | 0.83 | SLC1A3 (0.37) | TRPV4CA1CA2PTGES2CA12 | |
| SCHEMBL29835175 | 0.83 | SLC1A3 (0.37) | TRPV4CA1CA2PTGES2CA12 | |
| SCHEMBL3912870 | 0.82 | TRPV4 (0.46) | TRPV4CA1CA2CA9PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |