Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 4/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238601 | 1.00 | SCN1A (0.43) | SCN1ASCN5ASCN8APNMTNR1I2 | |
| SCHEMBL20237962 | 0.83 | SCN1A (0.45) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL29668759 | 0.83 | SCN1A (0.45) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL29668794 | 0.79 | OPRL1 (0.42) | SCN1ASCN5ASCN8APNMTOPRL1 | |
| SCHEMBL20238202 | 0.79 | OPRL1 (0.42) | SCN1ASCN5ASCN8APNMTOPRL1 | |
| SCHEMBL29669166 | 0.77 | KDM4E (0.58) | PNMTCYP2A13CXCR4KDM4EALDH1A1 | |
| SCHEMBL20238189 | 0.77 | KDM4E (0.58) | PNMTCYP2A13CXCR4KDM4EALDH1A1 | |
| SCHEMBL28740424 | 0.77 | SCN1A (0.39) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20237738 | 0.76 | KDM4E (0.42) | SCN1ASCN5ASCN8ANR1I2SCN1B | |
| SCHEMBL20238546 | 0.74 | SCN1A (0.45) | SCN1ASCN5ASCN8ANR1I2SCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |