Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238189 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL20256851 | 0.86 | CYP2A13 (0.69) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL20238193 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL29668956 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL20256476 | 0.83 | ALDH1A1 (0.58) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL20238341 | 0.80 | ALDH1A1 (0.57) | KDM4EALDH1A1POLBCYP2A13PRMT6 | |
| Methylamine SCHEMBL20238761 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1POLBCYP2A13PRMT6 | |
| SCHEMBL23851311 | 0.78 | SIGMAR1 (0.72) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL20238601 | 0.77 | SCN1A (0.43) | KDM4EALDH1A1POLBCXCR4CYP2A13 | |
| SCHEMBL29669190 | 0.77 | SCN1A (0.43) | KDM4EALDH1A1POLBCXCR4CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |