Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345097 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL28535540 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL1121573 | 0.80 | — | — | |
| SCHEMBL1412612 | 0.79 | ACP1 (0.41) | ACP1FDPSCYP2C19SLC6A3ALDH1A1 | |
| Ethane SCHEMBL28789069 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28858634 | 0.77 | ACP1 (0.41) | ACP1FDPSCYP2C19SLC6A3ALDH1A1 | |
| Alcohol SCHEMBL27675013 | 0.77 | FDPS (0.42) | FDPSSLC6A3ALDH1A1PKMLMNA | |
| Hydrochloric Acid SCHEMBL28585523 | 0.76 | ACP1 (0.45) | ACP1FDPSCYP2C19SLC6A3ALDH1A1 | |
| SCHEMBL3093696 | 0.67 | CYP2C19 (0.43) | ACP1FDPSCYP2C19SLC6A3ALDH1A1 | |
| SCHEMBL27557745 | 0.67 | ACP1 (0.44) | ACP1FDPSALDH1A1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114732910-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-07-12 | — | — | CN | disclosed |