Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095344 | 1.00 | SCN9A (0.46) | SCN9ASOS1MAPTTP53KDM4E | |
| SCHEMBL16109346 | 0.92 | SCN9A (0.48) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL19627592 | 0.91 | SCN9A (0.43) | SCN9ASOS1MAPTTP53MEN1 | |
| SCHEMBL1109044 | 0.90 | SCN9A (0.47) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL19631763 | 0.89 | SCN9A (0.46) | SCN9AMAPTTP53MEN1KMT2A | |
| SCHEMBL325911 | 0.89 | SCN9A (0.46) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL20449150 | 0.89 | SCN9A (0.46) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL20449236 | 0.88 | SCN9A (0.46) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL29736437 | 0.88 | SCN9A (0.40) | SCN9AMAPTTP53KDM4EMEN1 | |
| SCHEMBL1093593 | 0.88 | SCN9A (0.40) | SCN9AMAPTTP53KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |