SCHEMBL325911

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16109346	0.92	SCN9A (0.48)	SCN9AMEN1KMT2ATP53TAS2R14
	SCHEMBL1109044	0.90	SCN9A (0.47)	SCN9AMEN1KMT2ATP53TAS2R14
	SCHEMBL1095344	0.89	SCN9A (0.46)	SCN9AMEN1KMT2ATP53TAS2R14
	SCHEMBL29669273	0.89	SCN9A (0.46)	SCN9AMEN1KMT2ATP53TAS2R14
	SCHEMBL17048645	0.88	SCN9A (0.49)	SCN9AMEN1KMT2ATP53TAS2R14
	SCHEMBL14921517	0.87	SCN9A (0.45)	SCN9AMEN1KMT2ATP53POLB
	SCHEMBL31093304	0.87	SCN9A (0.45)	SCN9A
	SCHEMBL319158	0.87	SCN9A (0.45)	SCN9A
	SCHEMBL14699068	0.87	SCN9A (0.46)	SCN9AMEN1KMT2APOLBGAA
	SCHEMBL30479339	0.85	SCN9A (0.43)	SCN9AMEN1KMT2ATP53TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.