Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509290 | 0.83 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL3354917 | 0.83 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL11565380 | 0.83 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL27651310 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| Ammonia Solution, Strong SCHEMBL28268609 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| Phosphine SCHEMBL28283987 | 0.82 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL11791524 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL31195404 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL28193317 | 0.80 | HSD17B10 (0.45) | HSD17B10TDP1ALDH1A1POLBTSHR | |
| SCHEMBL8066554 | 0.80 | HSD17B10 (0.45) | HSD17B10TDP1ALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | HSD17B10 2296/4885TDP1 2063/4885ALDH1A1 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.