Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022679 | 0.90 | PARP1 (0.34) | PARP1ERN1 | |
| SCHEMBL7484218 | 0.80 | PARP1 (0.60) | PARP1ERN1 | |
| SCHEMBL29952788 | 0.80 | PARP1 (0.60) | PARP1ERN1 | |
| SCHEMBL31550049 | 0.77 | PARP1 (0.33) | PARP1ERN1 | |
| SCHEMBL10544843 | 0.75 | ERN1 (0.42) | PARP1ERN1 | |
| SCHEMBL10793189 | 0.75 | ERN1 (0.38) | PARP1ERN1CYP2A6 | |
| SCHEMBL28159711 | 0.73 | ERN1 (0.38) | PARP1ERN1 | |
| SCHEMBL3642305 | 0.72 | PARP1 (0.46) | PARP1ERN1CYP2A6 | |
| SCHEMBL28358041 | 0.72 | PARP1 (0.42) | PARP1 | |
| SCHEMBL10039710 | 0.71 | ERN1 (0.52) | PARP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478447-B | Benzo oxygen-containing ring derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114478447-A | Benzo-oxygen-containing ring derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |